cesarean section under general anesthesia
Conditions
Interventions
Esketamine:0.25mg/kg Esketamine
Sponsors
Department of Anaesthesiology, the International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Female
Age
25 Years to 35 Years
Inclusion criteria
Inclusion criteria: Singleton, ASA I-II, age 25-35 years, gestational age 38-40 weeks, body weight 55-75kg, body mass index 20-25kg /m2.
Exclusion criteria
Exclusion criteria: Known allergy to anesthesia inducers, liver and kidney dysfunction, cardiac insufficiency, diabetes mellitus, gestational hypertension, opioid allergy or long-term use of opioids, infection risks such as fever and leukocytosis before operation, perinatal accidents (massive blood loss, etc.), breast development defects, breast feeding contraindications (syphilis, hepatitis, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;Blood pressure;Apgar score;VAS score;Oxygen partial pressure;Partial pressure of carbon dioxide;PH value;Umbilical artery and vein blood drug concentration; | — |
Countries
China
Contacts
Public ContactYu-Chien Chao
Department of Anaesthesiology, the International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed