Efficacy of endoscopic radiofrequency for treatment of reflux hypersensitivity

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045014

Enrollment

Unknown

Registered

2021-04-03

Start date

2021-04-26

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reflux hypersensitivity

Interventions

teratment:endoscopic radiofrequency

control group:Sham-therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.More than 18 ages; 2.Meet the criteria of reflux hypersensitivity according to Rome IV; 3.Voluntarily participate in the clinical trial and sign the informed consent; 4.Agree to be treated and evaluated according to the requirements of the study protocol.

Exclusion criteria

Exclusion criteria: 1. Cardiac chest pain; 2. Intolerable gastroscopy; 3. History of gastrointestinal surgery; 4. Eosinophilic esophagitis; 5. Achalasia of cardia; 6. Outflow tract obstruction at esophagogastric junction; 7. Esophageal contraction disorder; 8. Distal esophageal spasm; 9. Hiatal hernia > 2cm; 10. Complicated with esophagogastric varices, severe heart, liver and kidney diseases; 11. After pacemaker implantation; 12. Coagulation therapy Blood dysfunction; 13. Severe sleep apnea syndrome; 14. Pregnant women.

Design outcomes

Primary

Measure	Time frame
Symptom score;	—

Secondary

Measure	Time frame
drug consumption;satisfication;PH;LES pressure;	—

Countries

China

Contacts

Public ContactJiang Yuanxi

Shanghai Tongji Hospital

jyxqrh@163.com+86 18916627762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026