subsolid nodules
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, gender is not limited; 2. Patients who plan to undergo complete resection of lung nodules or needle biopsy in our hospital; 3. Preoperative thin-slice CT examination found that the diameter of subsolid nodules of a single lung is <= 3cm ; 4. No history of malignant tumors in the past 5 years, and no neoadjuvant treatment before surgery; 5. No distant metastasis or patients with pleural and ascites found in preoperative evaluation; 6. The pathological diagnosis was clear after surgery; 7. Voluntary to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Imaging examination cannot be performed due to pregnancy, breastfeeding, etc.; 2. No thin-slice CT examination records in the clinical center receiving treatment at the time of enrollment evaluation; 3. With a history of lung infection one month before enrollment; 4. Have received blood transfusion treatment one month before enrollment, or have a history of alcohol or drug abuse; 5. Patients who cannot obtain enough blood samples (>=12ml); 6. Any conditions that are not suitable for blood sampling, such as anemia, fever, low autoimmunity, insufficiency of blood coagulation, etc.; 7. Patients with autoimmune diseases, blood system diseases, and infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Area under receiver operating curve (AUC);Sensitivity;Specificity; | — |
Countries
China
Contacts
Shanghai Pulmonary Hospital Affiliated to Tongji University