Alzheimer's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >= 65 years; 2. With diagnosis of probable AD based on the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimers Disease and Related Disorders Association (NINCDS-ADRDA) criteria; 3. Clinical Dementia Rating (CDR) score < 2.
Exclusion criteria
Exclusion criteria: 1. With severe hearing loss; 2. With obvious difficulty in communication; 3. With significant physical problems which disturb assessments or interventions; 4. With other problems which disturb assessments or interventions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| delayed recall of the World Health Organization University of California-Los Angeles, Auditory Verbal Learning Test (WHO-UCLA AVLT); | — |
Secondary
| Measure | Time frame |
|---|---|
| analysis of fractional amplitude of low- frequency fluctuation(fALFF) and functional connectivity(FC) of the resting-state fMRI; | — |
Countries
China
Contacts
Beijing Geriatric Hospital