Comparison of pharmacodynamics between ciprofol and propofol

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044963

Enrollment

Unknown

Registered

2021-04-03

Start date

2021-05-01

Completion date

Unknown

Last updated

2021-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia

Interventions

Control group:Propofol

Treatment group:Ciprofol

Eligibility

Sex/Gender

All

Age

20 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1.ASA I-II level; 2.Age 20-59 years old; 3.Plan to perform elective distal upper extremity orthopedic surgery; 4.The operation uses ultrasound to guide the lower brachial plexus block; 5.The patient agrees to use sedation during the operation.

Exclusion criteria

Exclusion criteria: 1.Cardiopulmonary dysfunction, liver and kidney dysfunction, hypoproteinemia; 2.Women during pregnancy and lactation; 3.Allergy to propofol has occurred in the past; 4.Have taken morphine and other analgesics recently (within 2 weeks); 5.Regional block anesthesia fails; 6.Cognitive dysfunction; 7.Obesity (body mass index > 30kg/M2); 8.Difficulty in percutaneous venipuncture (trying more than 2 times).

Design outcomes

Primary

Measure	Time frame
Hemodynamic and respiratory parameters (HR, Sp02, ECG, SBP, DBP, MAP);	—

Secondary

Measure	Time frame
Brain electrical activity parameters;Pain response parameter;Drug duration parameters;	—

Countries

China

Contacts

Public ContactZhu Feng

Panzhihua Hospital of Integrated Chinese and Western Medicine

28261691@qq.com+86 18096307251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026