Diabetes
Conditions
Interventions
Sodium alginate intervention group:Consume 5 g/d sodium alginate
Blank control group:None
Sponsors
Institute of Nutrition and Health, Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Fasting plasma glucose is 5.6~6.9 mmol/L, or glycosylated hemoglobin is 5.7%~6.4%, or 2-h plasma glucose during 75 g oral glucose tolerance test is 7.8~11.0 mmol/L; 2.The age is 18~70 years old; 3.Signing the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1.Suffering from cardiovascular disease, liver disease, kidney disease or malignant tumor; 2.Had dietary fiber supplements in the past six months; 3.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fasting plasma glucose;glycosylated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood glucose (mmol/L) × fasting insulin (µU/mL) / 22.5 (HOMA-IR);20×fasting insulin (µU/mL)/[fasting blood glucose (mmol/L)-3.5] (HOMA-ß);Blood lipid index;Serum and fecal metabolomics;Gut microbiome;Oxidative stress and inflammation factor; | — |
Countries
China
Contacts
Public ContactXiong Ke
Institute of Nutriton and Health, Qingdao University
Outcome results
None listed