Malignant Pleural Effusion
Conditions
Interventions
Group 1:bendable thoracoscopic conventional biopsy
Group 2:traditional ultrasound guided pleural biopsy
Group 3:ultrasound elastography-guided pleural biopsy
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with pleural effusion of unknown origin (with negative result of pleural effusion aspiration fluid); 2.Signed informed consent; 3.Patients must have preoperative chest CT, pleural fluid biochemical examination, pleural fluid cytology and other data.
Exclusion criteria
Exclusion criteria: 1.Patients with pleural effusion cytology suggesting "high suspicion" (unless the patient's cytological examination results are inconsistent with clinical manifestations and CT examination); 2.Pleural effusion cytology proves to be malignant; 3.Patients with severe pleural adhesions who cannot undergo medical thoracoscopy, and will not be randomized and if they signed informed consent, an elastic ultrasound-guided biopsy can be performed as a subgroup; 4.With severe cardiopulmonary dysfunction, poor general condition and so on, the patients cannot tolerate closed pleural biopsy; 5.With coagulation dysfunction; 6.Leakage; 7.Aged < 18 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic yield;Incidence of postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time; | — |
Countries
China
Contacts
Public ContactHou Gang
China-Japan Friendship Hospital
Outcome results
None listed