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Comparison of endometrial receptivity between GnRH-antagonist protocol and GnRH-agonist protocol in normal ovarian responders: a randomized controlled trial

Comparison of endometrial receptivity between GnRH-antagonist protocol and GnRH-agonist protocol in normal ovarian responders: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044921
Enrollment
Unknown
Registered
2021-03-31
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Group A:GnRH-antagonist propotol
Group B:GnRH-agonist long propotol

Sponsors

Guangdong Women and Children Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 37 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 20 and 6,FSH 1.11ng/mL; 3. BMI=18-28kg/m^2; 4. Couples with indications for in vitro fertilization-embryo transfer or intracytoplasmic sperm injection; 5. The couples who fully understand andparticipate in the experimental project voluntarily.

Exclusion criteria

Exclusion criteria: 1. There are serious factors affecting embryo implantation: hydrosalpinx, uterine adenomyosis, intrauterine adhesions, uterine malformations, III and IV endometriosis, etc; 2. Patients with PCOS; 3. Patients with repeated implanting failure; 4. Patients with uncured endometrial diseases; 5. Patients with alcoholism, malignant tumors and mental disorders; 6. Patients with cardiovascular, liver, kidney, hematopoietic and other serious life-threatening primary diseases.

Design outcomes

Secondary

MeasureTime frame
Number of retrieved oocytes;Incidence of moderate and severe OHSS;Optimal number of embryo;Normal fertilization rate;

Primary

MeasureTime frame
Clinical pregnancy rate;Implantation rate;

Countries

China

Contacts

Public ContactLiu Fenghua

Guangdong Women and Children Hospital

liushine2006@163.com+86 13926478318

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026