arthrophlogosis
Conditions
Interventions
Experimental group:Push dexamethasone 10mg statically for three times
Control group:None
Sponsors
Xi'an Honghui Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Receiving Total knee or hip arthroplasty; 2.General anesthesia;ASA class I~II; 3.Informed consent and voluntary participation of patients.
Exclusion criteria
Exclusion criteria: 1.Alcohol or drug abuse; 2.Allergic to dexamethasone; 3.Age = 80 years old; 4.Any glucocorticoids taken in the past 3 months before the operation; 5.Any potent opioids taken in the past 7 days; 6.Liver or renal failure; 7.Serious heart disease (New York Heart Association [NYHA] functional classification >2) 8.A history of connective tissue diseases (rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score for postoperative nausea and vomiting;VAS score for pain;C-reactive protein;Interleukin-6;Fasting blood-glucose (FBG);Serum cortisol;Range of motion;Early surgical wound infection; | — |
Countries
China
Contacts
Public ContactXu Peng
Outcome results
None listed