Postoperative analgesia after thoracoscopic lobectomy
Conditions
Interventions
Ropivacaine + fentanyl group:Add 15 µg fentanyl to ropivacaine
Ropivacaine + sufentanil group:Add 5µg sufentanil to ropivacaine
Ropivacaine + dexmedetomidine group:Add 25µg dexmedetomidine to ropivacaine
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Obtain written informed consent; 2.Patients scheduled for thoracoscopic lobectomy in our hospital; 3.Patients with American Society of Anesthesiologists (ASA) physical status classes I and II, aged 18 to 65 years; 4.Body Mass Index between 18.5 and 28 kg/m^2; 5.No obvious abnormalities in cardiopulmonary; 6.No obvious abnormalities in liver and kidney function and coagulation function.
Exclusion criteria
Exclusion criteria: 1.Puncture failed; 2.Local infection at the puncture site; 3.Thoracic and spinal deformity; 4.Histoy of allergy to local anesthetics and analgesics; 5.Surgery again within three days after surgery; 6.Refuse to participate in the study; 7.Change the procedure. 8.History of neuropsychiatric disease; 9.History of acute or chronic pain and analgesic drugs; 10.Tumor metastasis to other organs; 11.History of chemoradiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of analgesia;Resting and cough VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea;Postoperative vomiting;Pruritus;Urinary retention;Respiratory depression; | — |
Countries
China
Contacts
Public ContactSong Zhenguo
Tianjin Medical University Cancer Institute and Hospital
Outcome results
None listed