posterior circulation cerebral infarction
Conditions
Interventions
control group:reperfusion therapy
observation group:reperfusion combined with neuroprotective therapy
Sponsors
The First Affiliated Hospital of Suzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.The diagnosis was in accordance with the diagnostic criteria for acute cerebral infarction - posterior circulation cerebral infarction in the Chinese guidelines for the diagnosis and treatment of acute ischemic stroke 2018; 2.The age was 18-80 years old; 3.The patient received intravenous thrombolysis (and / or mechanical thrombectomy) within 6 hours of stroke onset; 4.the patient or his family members signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Intracranial hemorrhage, previous history of intracranial hemorrhage; 2.History of severe head injury or stroke, intracranial tumor or giant intracranial aneurysm in recent 3 months; 3.Intracranial or intraspinal surgery in recent 3 months; 4.Active visceral hemorrhage; 5.Large surgical operation in recent 2 weeks or arterial puncture in recent 1 week; 6.Unknown onset time of symptoms; 7.Rapid improvement of symptoms or mild symptoms before thrombolytic therapy MS >= 3 before onset; 8.Severe stroke (NIHSS score > 24), large area infarction on CT or MRI; 9.Pregnant, pregnant planning or lactating women; 10.Patients with known allergy or contraindication to the drug components in this study; 11.Patients with severe liver insufficiency, renal insufficiency and cardiac insufficiency; 12.Life expectancy of patients with malignant tumor < 6 months; 13.Autoimmune diseases and blood system diseases; 14.Patients with acute cerebral infarction in anterior circulation area; patients participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin 2,4, 6, 10, 17A;tumor necrosis factor a;Interferon ?;Immunization package; | — |
Countries
China
Contacts
Public ContactFang Qi
The First Affiliated Hospital of Suzhou University
Outcome results
None listed