Gastroscopy diagnosis and treatment
Conditions
Interventions
Test group 1:Intravenous injection of Ciprofol 0.2mg/kg
Test group 2:Intravenous injection of Ciprofol 0.4mg/kg
Control group:Intravenous injection of propofol 1mg/kg
Sponsors
Affiliated Cancer Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 60 to 80 years, regardless of gender; 2.Patients who received routine gastroscopy; 3.ASA score was grade I or grade II; 4.18 kg/m^2 < BMI < 30kg / m^2; 5.They clearly understood and volunteered to participate in the study, and the informed consent form was signed by them.
Exclusion criteria
Exclusion criteria: 1.Patients undergoing endotracheal intubation (including laryngeal mask); 2.Acute heart failure; unstable angina pectoris; myocardial infarction within 6 months before screening; resting ECG heart rate = 160mmHg or = 100mmHg). 9.Patients are allergic or contraindicated to benzodiazepines, opioids, propofol and their drug components; 10.Have participated in clinical trials of other drugs as subjects in the past 3 months; 11.The researchers believe that patients should not participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation induction time;Calm recovery time;Discharge time;Sedative hypotension rate;Incidence of respiratory depression during sedation;Satisfaction scores of anesthesiologists, endoscopists and patients;Incidence of abnormal heart rate events;Incidence of blood pressure fluctuation events;Incidence of other adverse events during entering the examination room-leaving the recovery room; | — |
Countries
China
Contacts
Public ContactYi Qianglin
Affiliated Cancer Hospital of Guizhou Medical University
Outcome results
None listed