Severe osteoarthritis of the knee
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 40 to 80 years; 2.American Society of Anesthesiologists (ASA) physical status score of I or III; 3.Body mass index (BMI) between 18.5 and 40 kg/m^2.; 4.Undergoing TKA, and willingness to receive CFNB for analgesia.
Exclusion criteria
Exclusion criteria: 1.Allergy to ropivacaine or other drugs used in this trial; 2.A history of opioid abuse or analgesic dependence; 3.Peripheral neuropathy; 4.History of chronic pain treatment; 5.Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative local anesthetics consumption 48 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numericalrating scale;Muscle strength score ;PCA frequency;Analgesia satisfaction;Cumulative Tramadol consumption;Time to first walk;Discharge time;Adverse reaction; | — |
Countries
China
Contacts
The First Affiliated Hospital of USTC Anhui Provincial Hospital