Acute type A aortic dissection
Conditions
Interventions
Elevated brain injury index group:None
Normal brain damage index group:None
Sponsors
Guangdong Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
16 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. Onset of disease <= 2 weeks; 3. Type A aortic dissection confirmed by CT angiography; 4. Willingness to receive surgery.
Exclusion criteria
Exclusion criteria: 1. Emorrhage/ischemic stroke or other intracranial lesions; 2. With history of brain tumor or other malignant tumors; 3. With brain infection or traumatic brain injury; 4. With neurodegenerative disease, demyelinating disease, Parkinson disease, Alzheimer disease or epilepsy; 5. With connective tissue diseases with nerve system involvement; 6. With pulmonary encephalopathy or hepatic encephalopathy; 7. Recent (= 6 months) oral/intravenous use of corticosteroids; 8. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glial fibrillary acidic protein (GFAP);Ubiquitin carboxy-terminal hydrolase L1(UCH-L1); | — |
Secondary
| Measure | Time frame |
|---|---|
| In-hospital mortality;Incidence of perioperative cerebral vascular events;Incidence of delirium;Postoperative 30-days all cause mortality; | — |
Countries
China
Contacts
Public ContactLi Xin
Guangdong Provincial People's Hospital
Outcome results
None listed