Postoperative pulmonary complications
Conditions
Interventions
PCV-VG:Ventilated with PCV-VG mode
PCV:Ventilated with PCV mode
VCV:Ventilated with VCV mode
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Selective cardiac surgery will be performed in the median sternal incision under the extracorporeal circulation; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Operations with deep hypothermia and circulatory arrest; 2. Heart transplantation, pulmonary thrombus endarterectomy; 3. Self-reported pregnancy; 4. Preoperative long-term use of hormone systemic therapy >= 3 months; 5. Already joined other similar research in recent 3 months; 6. Preoperative mechanical ventilation within 60 days of surgery, use of a double-lumen endotracheal tube or one-lung ventilation; 7. Neuromuscular dysfunction; 8. Preoperative extracorporeal membrane oxygenation support or ventricular assist device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative pulmonary complications, including respiratory failure, atelectasis, pulmonary infection, pneumothorax, pleural effusion, acute respiratory distress syndrome, aspiration pneumonia, bronchospasm, pulmonary embolism, and cardiogenic pulmonary edema; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative mechanical ventilation duration;LOS(length of stay);All-cause mortality;Severity degree of PPCs;ICU stay; | — |
Countries
China
Contacts
Public ContactYu Hai
Outcome results
None listed