Degenerative disease of the lumbar spine
Conditions
Interventions
Cocktail group:Local multifunctional cocktails +PCA (saline)
Control group:Local normal saline +PCA (analgesic)
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 80 years; 2. Participants with lumbar vertebral disc herniation, lumbar spinal stenosis or lumbar spondylolisthesis; 3. Participants undergoing posterior lumbar interbody fusion (PLIF); 4. Participants who provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Participants combined with lumbar tumour, tuberculosis, infection or lumbar vertebral fracture caused by trauma; 2. Participants with abnormal mental behaviour; 3. Participants with severe cardiac or respiratory disease and renal or hepatic dysfunction; 4. Participants who have undergone lumbar surgery in the past; 5. Participants allergic to any drug in the cocktail recipe; 6. Participants with abnormal coagulation function; 7. American Society of Anaesthesiologists (ASA) physical status > III; 8. Participants who have taken anti-platelet aggregates, such as aspirin or anticoagulants, in the last month; 9. Participants with histories of thromboembolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;Postoperative bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative bleeding;Coagulation function;Analgesic dosage; | — |
Countries
China
Contacts
Public ContactWei Jiang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed