Peri-implantitis and peri-implant mucositis
Conditions
Interventions
Photodynamic therapy group (Peri-implant mucositis):Photodynamic therapy
Minocycline hydrochloride group (Peri-implant mucositis):Minocycline hydrochloride
Photodynamic therapy + guided bone regeneration group (peri-implantitis):Photodynamic therapy + guided bone regeneration
Minocycline hydrochloride + guided bone regeneration group (peri-implantitis):Minocycline hydrochloride + guided bone regeneration
Sponsors
The Stomatology Hospital Affiliated to Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Aged >= 18 years. 2.Crown restoration for more than 1 year. 3.Follow the diagnostic criteria of the 2017 World Congress to the Classification of Periodontal and Peri-implant Diseases and Condition and be diagnosed as peri-implantitis or peri-implant mucositis. 4.Signed Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1.Various serious systemic diseases, oral infections, mental disorders, pregnancy/lactation, and unsuitable for oral treatment; 2.A history of allergy to the experimental drug (tetracycline and methylene blue); 3.Peri-implant maintenance or mechanical debridement were performed within 6 months; 4.Local or systemic antibiotics were administered within 6 months; 5.The patient's general or mental state is not compatible to complete this experiment, or patients are unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding On Probing;Plaque index;Implant Stability Quotient;Marginal bone loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Community abundance and diversity; | — |
Countries
China
Contacts
Public ContactSi Misi
The Stomatology Hospital Affiliated to Zhejiang University School of Medicine
Outcome results
None listed