Application of ablation in corneal degeneration and recurrent corneal epithelial erosion

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044783

Enrollment

Unknown

Registered

2021-03-27

Start date

2021-04-01

Completion date

Unknown

Last updated

2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent corneal epithelial erosion

Interventions

Patients with recurrent corneal erosion syndrome:coblation

patients with salzmann's nodular degeneration:coblation

patients with spheroidal degeneration:coblation

patients with band keratopathy:coblation

Eligibility

Sex/Gender

All

Age

8 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with recurrent corneal erosion syndrome, Salzmann nodular keratosis, globular degeneration and banded degeneration were clinically diagnosed. 2. Patiences who voluntarily sign informed consent and promise to cooperate with follow-up. 3. The symptoms recurred and did not respond to medication.

Exclusion criteria

Exclusion criteria: 1. Complicated with systemic diseases such as diabetes, heart and brain diseases and psychosis. 2. Allergic to any drug ingredient in this test. 3. Scar constitution.

Design outcomes

Primary

Measure	Time frame
inflammation cell density;endothelium density;Corneal nerve density;Limbal Vogt fence density;Corneal fluorescein staining;vision;intraocular pressure;Pain score;photophobia;Conjunctival congestion score;Foreign body sensation score;	—

Countries

China

Contacts

Public ContactXiaodan Huang

Affiliated Second Hospital of Zhejiang University

huangxiaodan@zju.edu.cn+86 13867460142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026