One-lung Ventilation
Conditions
Interventions
Group 1:inhaling pure oxygen
Group 2:After rapid pretreatment, the fiO2 of OLV was 60%.
Group 3:FiO2 60% after controlled pulmonary hyperplasia tube drawing.
Group 4:Early postoperative lung extension exercise, balloons were blown in PACU after surgery.
Group 5:After pretreatment, the total FIO of OLV was 260%, and controlled pulmonary inflation at the end of OLV. After the first Blow up a balloon for a day.
Group 6:After pretreatment, the total FiO260% of OLV was achieved, and the OLV was finished 20 cmH2O, 5s at each time, 3s at intervals until lung recovery is satisfactory, and the last pulmonary swell
Group 7:Inhalation of pure oxygen 3 minutes prior to the start of OLV until the end of OLV and after controlled lung inflation FiO260% to extubation. Balloons were blown in PACU after surgery.
Group 8:After pretreatment, the fiO of the whole OLV was 260%, and the controlled increase was achieved at the end of OLV Lung, balloon blowing in PACU after surgery.
Sponsors
Department of Anesthesiology, Nanfang Hospital Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. 90 adult patients undergoing elective thoracoscopic lobectomy; 2. Aged from 18 to 70 years; 3. American association of anesthesiologists classified as grade I or II; 4. no history of thoracic surgery and radiotherapy; 5. no complication of other malignant tumors; 6. non-small cell lung cancer; 7. no special abnormality in preoperative pulmonary function examination.
Exclusion criteria
Exclusion criteria: 1. Chest X-ray showed that the transverse diameter of the trachea at the clavicular end of the sternum was less than 11mm; 2. Bronchial anatomical abnormalities were found by preoperative fiberoptic bronchoscopy; 3. Patients with inverted whole organs; 4. Cardiac function class III or IV; 5. Heart-related diseases; 6. Thrombocytopenia; 7. History of anesthetic allergy; 8. Family history of malignant hyperthermia; 9. Predictable and unpredictable difficult airway: Mallampati airway grade III or above, temporomandibular joint ankylosis or mouth opening difficulty, unable to insert DLT successfully. 10. Pregnancy or puerperium; 11. Peripheral vascular disease; 12. Coagulation dysfunction; 13. Patients with large amount of blood loss and blood transfusion during operation, patients with cardiopulmonary resuscitation; 14. Patients who need large dose of vasoactive drugs to maintain circulation; 15. Patients who cannot be extubated after operation and need to continue to use ventilator-assisted ventilation; 16. Patients who need secondary intubation or secondary operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative chest tube indwelling time;postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactYe Jing
Department of Anesthesiology, Nanfang Hospital Southern Medical University
Outcome results
None listed