Hip fracture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 65 to 85 years; 2. ASA classification is I and II; 3. Hip surgery; 4. The subjects (or their legal representatives) have signed the informed consent form.
Exclusion criteria
Exclusion criteria: The following patients cannot participate in this study: 1. There is a history of myocardial infarction or unstable angina pectoris, or atrioventricular block of degree II and above within 6 months, or a history of severe arrhythmia such as stagnation, or a history of NYHA heart function class II and above before screening ; 2. Past mental system diseases (such as schizophrenia, depression, etc.) and cognitive dysfunction, or a history of epilepsy,or a history of Parkinson's syndrome; 3. Subjects who have not received regular antihypertensive therapy or have poor blood pressure control (systolic blood pressure >= 160mmHg or = 100mmHg or = 11.1mmol/L; 5. Abnormal coagulation function during the screening period: prothrombin time (PT) prolonged beyond the upper limit of normal by 3 seconds and/or activated partial thromboplastin time (APTT) prolonged beyond the upper limit of normal by 10 seconds; 6. Consecutive taking opioid analgesics for more than 10 days, or the time of last taking the drug is less than the 5 half-life of the drug at random.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a numerical rating scale (NRS) score;Sensory block duration;Morphine consumption;Serum C-reactive protein (CRP) and interleukin-6 (IL-6); | — |
Countries
China
Contacts
Department of Anesthesiology, Subei People's Hospital of Jiangsu province