Surgery for hip fracture in elderly patients
Conditions
Interventions
Group I :Insulin 20 IU
Group C :Normal saline 0.5ml
Sponsors
The Third Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1.ASA score is I-III grade; 2.Aged over 65 years; 3.Elderly patients undergoing elective hip fracture repair are expected to have an operation lasting 1 hour or more.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of mental illness or family history of mental illness; 2.A history of long-term use of psychotropic drugs, chronic analgesics, corticosteroids, or alcohol abuse; 3.The score of preoperative Mini Mental State Examination (MMSE) was less than 15 points; 4.Severe impairment of hearing, vision and language functions; 5.Severe hepatic and renal insufficiency; 6.Patients with untreated or undertreated hyperthyroidism; 7.Patients who cannot receive general anesthesia or are allergic to anesthetic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of delirium 5 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of POCD 7 days after surgery;Serum concentrations of pro-inflammatory cytokines;postoperative hospital stays; | — |
Countries
China
Contacts
Public ContactLiu Peng
The Third Hospital of Hebei Medical University
Outcome results
None listed