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Reconstruction Strategy of Cerebral Spinal Fluid Leak during Endoscopic Endonasal Surgery (Grade I-II: in Situ Material Harvest for Reconstruction; Grade II-III: Cruciate Embedding Fascia-Bone Flap Technique)

Reconstruction Strategy of Cerebral Spinal Fluid Leak during Endoscopic Endonasal Surgery (Grade I-II: in Situ Material Harvest for Reconstruction; Grade II-III: Cruciate Embedding Fascia-Bone Flap Technique)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044764
Enrollment
Unknown
Registered
2021-03-27
Start date
2015-05-01
Completion date
Unknown
Last updated
2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary adenomas, craniopharyngiomas, meningiomas and other midline skull base tumors which are suitable forendoscopic endonasal surgery

Interventions

Cruciate Embedding Fascia-Bone Flap Technique:N/A
Pedicle Vascularized Nasoseptal Flap:N/A

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
22 Years to 72 Years

Inclusion criteria

Inclusion criteria: 1. Patient underwent endoscopic endonasal surgery in our hospital from May 2015 to May 2020; 2. Patient was confirmed with grade II-III cerebrospinal fluid leak during operation; 3. Patient was followed up at least 6 months; 4. Patient underwent cruciate embedding fascia-bone flap technique (CEFB) and / or pedicle vascularized nasoseptal flap(PNSF) during operation as skull base reconstruction.

Exclusion criteria

Exclusion criteria: 1. Patient was diagnosed with non-skull base midline tumors; 2. Patient with history of skull base fracture or operation; 4. Patient with poor health condition and could not tolerate the operation; 5. Patient with tumor recurrence.

Design outcomes

Primary

MeasureTime frame
Postoperative cerebrospinal fluid leakagePostoperative CSF leak;Infection;

Secondary

MeasureTime frame
Dysosmia;Nasal discomforts;Epistaxis;

Countries

China

Contacts

Public ContactWang Xiaoshu

Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University

xswang789@cqmu.edu.cn+86 13983762659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026