Elderly patients
Conditions
Interventions
control group 1:Induction of anesthesia with propofol injection
control group 2:Induction of anesthesia with etomidate injection
Sponsors
Changshu No.2 People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. 65 to 70 years old, no gender limit; 2. American Anesthesiologists (ASA) III; 3. Elderly laparoscopic cholecystectomy patients who need tracheal intubation for elective surgery; 4. Body mass index (BMI) >= 18 and = 10 and = 95% when breathing air; systolic blood pressure (SBP) >= 90mmHg and = 60mmHg and = 55 and <= 100 beats/min; 6. Able to understand the research process and methods, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Those who have general anesthesia contraindications or have a history of anesthesia accidents; 2. Those who are known or suspected to be allergic or contraindicated to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Patients with craniocerebral loss, intracranial hypertension, stroke, unstable angina, and myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, difficult airway, or difficulty in tracheal intubation (modified Markov score is III or IV); 5. Uncontrolled diabetes or hypertension; 6. Severe liver dysfunction or severe renal insufficiency; 7. History of alcohol abuse or drug dependence; 8. Abuse or long-term use of narcotic, sedative, and analgesic drugs; 8. Those who have a history of mental illness; 10. Those who have participated in any drug clinical trial within 1 month before screening; 11. Pregnant and lactating women; fertile women or men who are unwilling to use contraception during the entire trial period; subjects (including male subjects) who have pregnancy plans within 1 month after the trial; 12. The investigator believes that there are any other subjects who are not suitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthesia induction success rate; | — |
Countries
China
Contacts
Public ContactWang Meifang
Changshu No.2 People's Hospital
Outcome results
None listed