The value of gut microbiota and short-chain fatty acids in predicting necrotizing enterocolitis in premature infants

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044736

Enrollment

Unknown

Registered

2021-03-26

Start date

2021-06-01

Completion date

Unknown

Last updated

2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal necrotizing enterocolitis

Interventions

Group Non-NEC:No

Group NEC with surgery:No

Group NEC without surgery:No

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Newborns with a gestational age of less than 34 weeks with high-risk factors for NEC (abdominal distension, vomiting, diarrhea, elevated infection indicators, etc.) admitted to the Neonatal Diagnosis and Treatment Center of Children's Hospital of Chongqing Medical University.

Exclusion criteria

Exclusion criteria: 1. Children who die during hospitalization due to non-NEC; 2. Children with congenital gastrointestinal malformations (such as congenital intestinal atresia, megacolon, intestinal malrotation, etc.); 3. Children who give up treatment during hospitalization ; 4. Children who have not completed the determination of gut microbiota and SCFAs; 5. Children who do not want to participate in this study.

Design outcomes

Primary

Measure	Time frame
gut microbiota;short-chain fatty acids;Blood Routine;Abdominal imaging;	—

Countries

China

Contacts

Public ContactLi Luquan

Children's Hospital of Chongqing Medical University

liluquan123@163.com+86 17323882725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026