End-stage renal disease stage 5
Conditions
Interventions
Group 1 vs. Group 2: Idavir and Baxter peritoneal dialysis solution
Sponsors
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years, no gender limit; 2. Diagnosed as end-stage renal disease; 3. The peritoneal dialysis treatment mode is CAPD; 4. Peritoneal dialysis time >= 30 days or new start of peritoneal dialysis; 5. Be able to perform standard home dialysis treatment; 6. Sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Acute renal failure; 2. Prepare to receive a kidney transplant within half a year; 3. Hemodialysis; 4. There is acute or chronic exit infection or tunnel infection; 5. Suffered from peritonitis 30 days before the screening visit (2 out of 3 conditions are met, hereinafter referred to as peritonitis): (1) Abdominal pain, turbid ascites, with or without fever; (2) The white blood cell count in the exudate > 100 x 10^6/L, and the proportion of neutrophils > 50%; (3) The growth of pathogenic microorganisms in the permeate; 6. Known allergy to peritoneal dialysate components; 7. Suffering from other serious diseases such as active, or treated residual malignant tumor or systemic infection, liver cirrhosis, congestive heart failure, anemia (Hb 100kg or weight < 40kg); 9. Poor compliance, unable to treat according to the plan; 10. Pregnant or breast-feeding, women of childbearing age do not agree to use effective contraceptive measures during the trial; 11. History of alcohol and drug abuse (defined as the use of illegal drugs); 12. Any other circumstances in which the investigator believes that the patient cannot join the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrafiltration capacity;Urea clearance index; | — |
Countries
China
Contacts
Public ContactXu Dongmei
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)
Outcome results
None listed