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Clinical study of nalbuphine combined with ropivacaine for abdominal transverse muscle plane block for analgesia after cesarean section

Clinical study of nalbuphine combined with ropivacaine for abdominal transverse muscle plane block for analgesia after cesarean section

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044718
Enrollment
Unknown
Registered
2021-03-26
Start date
2020-06-15
Completion date
Unknown
Last updated
2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical study of postoperative analgesia in cesarean section

Interventions

Group1:Add 20mg nalbuphine to local anesthetic for transverse abdominal plane block (bilateral)
Group2:Add 30mg nalbuphine to local anesthetic for transverse abdominal plane block (bilateral)
Group3:Simple transverse abdominis plane block

Sponsors

Liaocheng People's Hospita
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing cesarean section; 2. American Society of Anesthesiologists (ASA) grade II~III; 3. Aged 20 ~ 35 years old, weight 50-90kg.

Exclusion criteria

Exclusion criteria: 1. Those allergic to nalbuphine and ropivacaine; 2. Damaged skin infection at the puncture site; 3. Mental abnormalities; 4. Have obvious heart, lung, liver and kidney insufficiency; 5. Cannot use the numerical rating scale (NRS) score of pain; 6. Those who refuse to perform nerve block.

Design outcomes

Primary

MeasureTime frame
Postoperative resting and activity NRS scores;Pain location: visceral pain or body surface pain;Postoperative analgesics (including PCIA dosage and additional analgesics in the ward);

Secondary

MeasureTime frame
Nerve block plane;Intestinal motility recovery time, eating time, getting out of bed activity time;Patient comfort, postoperative adverse reactions, satisfaction with postoperative analgesia and postoperative recovery;

Countries

China

Contacts

Public ContactAi'lan Yu
yuercai@126.com+86 13563530309

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026