Alveolar bone defect after tooth extraction operation
Conditions
Interventions
biological mesh produced by Beijing Ruijian Biotechnology Co., Ltd:biological mesh produced by Beijing Ruijian Biotechnology Co., Ltd
Geistlich Bio-Gid:Geistlich Bio-Gid
Sponsors
Beijing Chaoyang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged 18-70 years, gender unlimited; 2) Subjects requiring alveolar ridge preservation immediately after tooth extraction; 3) There are four bony walls in the tooth extraction fossa and at least one adjacent tooth; 4) During the study period, the subjects participated in the trial with single tooth; 5) Subjects are willing to participate in the test, and the subjects or their legal agent can sign in the ICF.
Exclusion criteria
Exclusion criteria: 1) Severe insufficiency of heart, liver and kidney; 2) Poor control of diabetes and hypertension; 3) Long-term use of non-steroidal anti-inflammatory drugs, bisphosphonates, corticosteroids, tetracycline, immunosuppressants and other drugs that affect bone metabolism or bone healing; 4) People with known history of allergy and specific allergy to pig-derived materials; 5) Subjects who refuse to use pig-derived medical products due to religious or ethnic reasons; 6) Participated in any clinical trials of drugs and/or medical devices within 3 months prior to the study; 7) Other circumstances in which the investigator considers the subject unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar bone width change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alveolar bone height change;The curative effect of soft tissue healing;Bone density and new bone profile evaluation; | — |
Countries
China
Contacts
Public ContactZuomin Wang
Beijing Chaoyang Hospital, Capital Medical University
Outcome results
None listed