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The Application of Intravenous Dexmedetomidine during PELD Under the Monitoring of RVM: a Prospective Observational Study

The Application of Intravenous Dexmedetomidine during PELD Under the Monitoring of RVM: a Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044715
Enrollment
Unknown
Registered
2021-03-26
Start date
2019-06-01
Completion date
Unknown
Last updated
2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oxidative stress

Interventions

Sponsors

The First Affiliated Hospital of Jiangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The clinical and radiographic lumbar disc; 2. Determine the height of prolapse percutaneous spine endoscopic surgery; 3. ASA I - II level; 4. Aged 20 ~ 60 years; 5. Body mass index of 18.5-23.9 kg/m2.

Exclusion criteria

Exclusion criteria: 1. There are local anesthetics, right the microphones will use contraindicated; 2. History of lung disease; 3. With lumbar instability, lumbar olisthe; 4. Has a history of spinal surgery or other organs recent surgery; 5. Merging neural, endocrine and metabolic disease and suffering from diseases such as heart, lung, liver, kidney or acute or chronic inflammation in recent activity.

Design outcomes

Primary

MeasureTime frame
minute ventilation volume;tidal volume;respiratory rate;mean arterial pressure;heart rate;pulse oxygen saturation;observer's assessment of alertness/sedation;visual analogue score;

Secondary

MeasureTime frame
interleukin-6;tumor necrosis factor-a;Malondialdehyde;glutathione peroxidase;

Countries

China

Contacts

Public ContactRe'ai Shan

The First Affiliated Hospital of Gannan Medical University

shanreai@163.com+86 13803587468

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026