Effects of esmolol on inflammatory cytokines and the quality of recovery in patients with severely burn wounds undergoing tangential excision skin grafting

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044713

Enrollment

Unknown

Registered

2021-03-26

Start date

2018-12-01

Completion date

Unknown

Last updated

2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burn

Interventions

experimental group:esmolol was pumped from anesthesia induction to extubation

control group:normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Aged 18-60 years old, ASA II-III, 31-50% of the total burn area, 11%-20% of III degree burn.

Exclusion criteria

Exclusion criteria: Past history of heart disease (sinus bradycardia, hypotension, conduction block, and preoperative ß-blockers or calcium channel blockers), liver and kidney failure, and history of asthma.

Design outcomes

Primary

Measure	Time frame
inflammatory cytokines;QoR-40 scores;	—

Secondary

Measure	Time frame
VAS scores;Intraoperative anesthetic dosage;Postoperative extubation time;PACU stay time;	—

Countries

China

Contacts

Public ContactQiu Jing

Jinhua Municipal Central Hospital

1265801961@qq.com+86 15067078990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026