Metabolic changes of bile acids with pregnancy progression and their correlation with perinatal complications in intrahepatic cholestasis of pregnancy patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044712

Enrollment

Unknown

Registered

2021-03-26

Start date

2020-02-10

Completion date

Unknown

Last updated

2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intrahepatic cholestasis of pregnancy

Interventions

intrahepatic cholestasis of pregnancy vs. normal controlled group:Nil

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) Aged over 18 years; (2) Gender:female; (3) Pregnant women; (4) Serum total bile acid over 10 µM/L

Exclusion criteria

Exclusion criteria: (1) In-vitro fertilization and embryo transfer; (2) Elevated liver enzymes and low platelets syndrome; (3) Multiple pregnancy; (4) Pre-eclampsia; (5) Family history of intrahepatic cholestasis of pregnancy.

Design outcomes

Primary

Measure	Time frame
Bile acids metabolism;	—

Secondary

Measure	Time frame
preterm birth;pre-eclampsia;gestational diabetes mellitus;	—

Countries

China

Contacts

Public ContactBo Zhu

Ethics Committee of Women's Hospital, School of Medicine, Zhejiang University

5202054@zju.edu.cn+86 15858261555

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026