fatty liver disease
Conditions
Interventions
Healthy Volunteer Group :No intervention
NAFL Group:No intervention
NASH Group:No intervention
NAFLD-related cirrhosis group :No intervention
Sponsors
The Sixth People's Hospital of Chengdu
Eligibility
Sex/Gender
All
Age
30 Years to 71 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-70, no gender limit; 2. Based on medical history, imaging, biochemistry, and endoscopy results, in line with the 2016 NAFLD clinical practice guidelines diagnostic criteria of the European Society of Hepatology, Diabetes Society and Obesity Association; 3. Nearly 3 months No gastrointestinal bleeding, spontaneous peritonitis, hepatic encephalopathy and other acute complications related to portal hypertension; 4. Liver disease caused by viruses, alcohol, drugs and autoimmunity are excluded; 5. No fasting in the past 3 months.
Exclusion criteria
Exclusion criteria: 1. Complicated with serious diseases of heart, lung and other organ systems; 2. Malignant tumors or other wasting diseases; 3. Acute complications of portal hypertension occurred in the past 3 months; 4. Intestinal probiotics had been used in the past 3 months Bacteria or antibiotics, which may affect the results; 5. Rheumatic immune diseases or bacterial infections and other systemic inflammations in the past 3 months; 6. Co-infections and other serious diseases; 7. History of smoking or drinking; 8. History of infectious diseases Or viral hepatitis markers, autoantibodies are positive; 9. The subject requires withdrawal; 10. The researcher thinks it is necessary to exclude or not to continue participating in the research;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood acetic acid;Blood propionic acid;Butyric acid; | — |
Countries
China
Contacts
Public ContactQian Xiang
The Sixth People's Hospital of Chengdu
Outcome results
None listed