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Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cells immunotherapy combined with chemotherapy in patients with colorectal cancer after surgery

Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cells immunotherapy combined with chemotherapy in patients with colorectal cancer after surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044702
Enrollment
Unknown
Registered
2021-03-26
Start date
2008-02-01
Completion date
Unknown
Last updated
2021-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

CIT group:CIK combined chemotherapy
SLAMF7+:IHC SLAMF7 Score 2-3
SLAMF7-:IHC SLAMF7 Score 0-1

Sponsors

Yan'an Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
39 Years to 87 Years

Inclusion criteria

Inclusion criteria: 1.Patients who underwent radical resection, pathologically confirmed primary colorectal adenocarcinoma; 2.Aged 18-80 years; 3.without chemotherapy or radiotherapy preoperative; 4.without severe autoimmune disease or immunodeficiency disease; 5.without infectious diseases syphilis or AIDS,without active hepatitis B or C; 6.cardiovascular, liver, kidney, coagulation functions are normal; 7.without other malignant tumors; 8.case data and information were complete.

Exclusion criteria

Exclusion criteria: 1.Combined with severe cardiovascular, liver, kidney disease or disfunction; 2.combined with other malignancies; 3.combined with autoimmune disease; 4.combined with syphilis or HIV infection; 5.combined with pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
Overall Survival;Progress-Free Survival;SLAMF7 IHC score;

Secondary

MeasureTime frame
serum tumor marker;

Countries

China

Contacts

Public ContactRuhong Li

Yan'an Affiliated Hospital of Kunming Medical University

lrh272@126.com+86 13888841925

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026