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The associations between interleukin-37 and relative cytokines in Infrapatellar fat pad and radiographic changes in knee osteoarthritis patients and review.

The associations between interleukin-37 and relative cytokines in Infrapatellar fat pad and radiographic changes in knee osteoarthritis patients and review.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044698
Enrollment
Unknown
Registered
2021-03-26
Start date
2019-01-30
Completion date
Unknown
Last updated
2021-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

OA group vs.control group:Nil

Sponsors

Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: The indication for all 20 patients undergoing TKR was: (1) osteoarthritis of the knee joint with at least grade 2 by Kellgren-Lawrence (K-L) grading system using Altman Atlas; (2) restrict joint activities. Patients in the osteoarthritis group must meet the following criteria: (1) knee OA histopathologically; (2) primary knee arthroplasty; (3) follow-up data were complete.

Exclusion criteria

Exclusion criteria: Cases met the following criteria would not be included in the study: (1) secondary knee arthroplasty; (2) patients also diagnosed diabetes, coronary heart disease or other severe condition or diseases; (3) knee infection or other autoimmune diseases occurred before the operation.

Design outcomes

Primary

MeasureTime frame
Inter'leukins;TNF-a;—

Secondary

MeasureTime frame
BMI;C--reaction protein;ESR;WOMAC scale;—

Countries

China

Contacts

Public ContactXie Xiaobo

Department of Orthopaedics, Zhujiang Hospital, Southern Medical University

1049053657@qq.com+86 18664663051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026