Methylmalonic aciduria
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Henan University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: (1) It was consistent with the diagnosis of cblC type MMA of deficiency of both heart and spleen; (2) For the clinical manifestations with abnormal language function, the assessment results of S-S language retardation test were referred to for the determination of language dysfunction; (3) They were aged from 1 to 5 years old; (4) The legal guardian of the child signed the informed consent and was willing to accept traditional Chinese medicine treatment and clinical investigation.
Exclusion criteria
Exclusion criteria: (1) There were severe visual impairment, hearing impairment, cardiovascular and cerebrovascular diseases; (2) Patients with other diseases that seriously affect language function, such as hypothyroidism and hydrocephalus; (3) Patients with severe infection, abnormal liver and kidney function and metabolic disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| S-S language retardation test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pedsqltm 4.0 universal core scale; | — |
Countries
China
Contacts
Public ContactZhang Fan
The First Affiliated Hospital of Henan University of traditional Chinese Medicine
Outcome results
None listed