peri-implant disease
Conditions
Interventions
experimental group:Place minocycline around the healing cap
control group:Nil
Sponsors
West China College of Stomatology Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy adult (18-65 years old); 2. The patient has missing teeth and requires implant restoration; 3. Complies with non-embedded healing (specifically, it can be determined according to the teachers own non-embedded healing standards): no bone graft in the near and far, No obvious soft group defect, glycosylated hemoglobin < 8%; 4. Good oral hygiene: full mouth plaque index <= 25%; full mouth bleeding index less than or equal to 25%.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breast-feeding; 2. Are taking drugs (phenytoin, cyclosporine or calcium channel blockers), warfarin or non-steroidal anti-inflammatory drugs that may affect the periodontal condition; 3. Suffering from uncontrollable systemic diseases; 4. Are allergic to tetracycline, are using chlorhexidine or other types of mouthwash, and have taken antibiotics within 3 months; 5. Smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Landry Wound-Healing Index;Inflammatory factor levels;peri-implant's microbial level; | — |
Secondary
| Measure | Time frame |
|---|---|
| peri-implant marginal bone level; | — |
Countries
China
Contacts
Public ContactQuan Yuan
West China College of Stomatology Sichuan University
Outcome results
None listed