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The role of immune cells in the process of glucocorticoid-induced osteoporosis and the therapeutic effect of mesenchymal stem cells

The role of immune cells in the process of glucocorticoid-induced osteoporosis and the therapeutic effect of mesenchymal stem cells

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044675
Enrollment
Unknown
Registered
2021-03-25
Start date
2021-03-20
Completion date
Unknown
Last updated
2021-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoporosis

Interventions

case series:Nil

Sponsors

The First Affiliated Hospital of Suzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) The age at the time of signing the informed consent form is between 18 and 70 years old (including both ends), regardless of gender. 2) The patients with autoimmune diseases were diagnosed according to the American Rheumatic Association (ACR) / European Rheumatic Union (EULAR) classification criteria of autoimmune diseases. 3) The course of treatment with any dose of glucocorticoid is expected to exceed 3 months.

Exclusion criteria

Exclusion criteria: 1) Have a history of lymphoproliferative disease, or may be various signs or symptoms of lymphoproliferative disease. 2) have a history of malignant tumor. 3) patients with a history of recurrent herpes zoster, disseminated herpes zoster or disseminated herpes simplex, or a random history of herpes zoster or herpes simplex within the first 2 months. 4) have mental or neurological diseases, unwilling to communicate or have language barriers, unable to fully understand and collaborate. 5) the researchers believe that there are any other factors that may affect the conduct of this study or the evaluation of the results.

Design outcomes

Primary

MeasureTime frame
Bone mineral density;Bone metabolism index;

Countries

China

Contacts

Public ContactWu Jian

The First Affiliated Hospital of Suzhou University

xinchang@suda.edu.cn+86 512-67780059

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026