Retrograde autologous priming of the cardiopulmonary bypass circuit reduces blood transfusion in adults: a prospective, randomized trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044655

Enrollment

Unknown

Registered

2021-03-25

Start date

2019-01-15

Completion date

Unknown

Last updated

2021-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Valvular heart disease

Interventions

Standards Group:Precharge the CPB line according to the standard

RAP Group:Priming the CPB line with retrograde autologous priming

Eligibility

Sex/Gender

All

Age

16 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The patients undergoing heart valve replacement surgery in our hospital; 2. Aged 16 to 70 years; 3. Elective surgery

Exclusion criteria

Exclusion criteria: 1. left ventricular ejection fraction less than 30%; 2. haemodynamic instability; 3. neurological deficits or a history of stroke; 4. preoperative heparin or warfarin therapy; 5. a preoperative HCT value less than 33% and estimated CPB time of at least 120 min.

Design outcomes

Primary

Measure	Time frame
Transfusion rate;hematocrit;	—

Secondary

Measure	Time frame
LACTIC ACID number;	—

Countries

China

Contacts

Public ContactRong-Quan Chen

Zhangzhou Municipal Hospital Affiliated to Fujian Medical University

crq-crs@163.com+86 15259608543

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026