Esophageal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Gastroscopy has been performed and there is a clear pathological diagnosis of esophageal cancer; 2) Aged 18 to 75 years; 3) ASA (American College of Anesthesiologists Patient Status Assessment Grade I ~ III); 4) Patients undergoing three-incision radical resection of esophageal cancer under elective general anesthesia; 5) No previous chest or abdominal surgery; 6) Lung function can tolerate endoscopic surgery, and the functions of heart, liver, kidney and other major organs are basically normal.
Exclusion criteria
Exclusion criteria: 1) Past history of severe hypertension, diabetes, liver and kidney diseases and allergic history of anesthetic drugs; 2) Patients with asthma or emergency operation; 3) Mental retardation and nervous system diseases; 4) Patients with severe heart disease and preoperative adjuvant radiotherapy and chemotherapy; 5) Participating in other clinical trials; 6) Patients with coagulation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operation time;Arterial blood gas analysis;Evaluation of lung collapse and surgical field;Vasoactive drug; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications;Tracheal mucosal injury (cuff pressure value);Anesthesia time;Anesthesia time; | — |
Countries
China
Contacts
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology