chronic kidney disease in stage 3-4
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) In accordance with the above western medical diagnostic criteria and TCM syndrome differentiation criteria (spleen and kidney deficiency, turbid toxin internal accumulation syndrome type), and CKD3-4 stage diagnostic criteria (eGFR calculation uses CKD-EPI formula); glomerular filtration rate in patients with glomerular filtration rate of 15: 59 mL/min; (2) Between 18 and 75 years old, regardless of sex; (3) Boluntarily participate in the clinical trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating women, those who are allergic and intolerant to drugs; (2) Patients with severe cardio-cerebrovascular disease or liver system disease or tumor, who are in a state of infection, bleeding tendency and mental illness; (3) Patients who are receiving hormone or immunosuppressive therapy for the primary disease or other diseases or who have received hormone or immunosuppressive therapy within 4 weeks have received renal replacement therapy: (4) Infection, acidosis, electrolyte disturbance and hypertension were not effectively controlled; (5) Patients with intestinal diseases. Such as Crohn's disease, irritable bowel syndrome, hemorrhoids, intestinal tumors, hernia, gastrointestinal bleeding, anal fissure and so on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| creatinine;eGFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| BUN;Uric acid;Cystatin C; | — |
Countries
China
Contacts
Longhua Hospital affiliated to Shanghai University of traditional Chinese Medicine