Effects of different anesthetic methods on perioperative gastrointestinal function in patients undergoing laparoscopic radical resection of gastrointestinal tumors

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044595

Enrollment

Unknown

Registered

2021-03-24

Start date

2021-04-01

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal neoplasms

Interventions

group 1:propofol induction and postoperative analgesia by opioid

group 2:esketamine induction and postoperative analgesia by esketamine

group 3:esketamine induction and esketamine maintenance and esketamine postoperative analgesia

group 4:esketamine induction and postoperative analgesia by opioid

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The patients who were scheduled for laparoscopic gastrointestinal tumor resection; 2. ASA grade I-III; 3. Aged 18-65 years; 4. education level above primary school; 5. signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative tumor metastasis; 2. Intestinal obstruction; 3. patients with severe heart, liver, kidney and other organic diseases; 4. pregnant or lactating women; 5. Patients with relevant contraindications for treatment; 6. Preoperative drugs affecting intestinal flora disorders.

Design outcomes

Primary

Measure	Time frame
gastrointestinal microorganism;cytokines;	—

Countries

China

Contacts

Public ContactJia Xuqin

The First Affiliated Hospital of Guangxi Medical University

jiaxuqin@21cn.com+86 13558108625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026