intestinal Behcet's disease
Conditions
Interventions
Single group:Endoscopic injection of triamcinolone acetonide
Sponsors
The First Affiliated Hospital of Sun Yat-Sen University,
Eligibility
Sex/Gender
All
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with Behcet's disease diagnosed in our hospital. The diagnostic criteria are in line with the diagnostic criteria for intestinal Behcet developed by the Korean IBD Cooperation Group in 2009. 1. Patients who have been ineffective after treatment with 5-aminosalicylic acid, corticosteroids, azathioprine or anti-tumor necrosis factor-a drugs for more than 8 weeks 2. Hormone dependent patients; 3. Number of ulcers <= 5.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from other intestinal diseases such as Crohn's disease, intestinal tuberculosis, infectious enteritis, non-specific colitis, drug-related colitis, etc.; 2. Patients taking large amounts of immunosuppressive agents and glucocorticoids; 3. Patients with severe liver and kidney dysfunction; 4. Patients with contraindications to glucocorticoids, such as allergy to glucocorticoids, recent gastrointestinal anastomosis, diabetes, severe systemic infection, active peptic ulcer, history of severe mental illness, severe osteoporosis, high blood pressure Grade III, tuberculosis, etc.; 5. Patients with cardiovascular or cerebrovascular diseases using oral anticoagulants or antiplatelets.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 8-week clinical remission rate and endoscopic mucosal healing rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 52-week clinical remission rate and endoscopic mucosal healing rate; | — |
Countries
China
Contacts
Public ContactHe Yao
The First Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed