Sedative and anti-anxiety effects of intranasal dexmedetomidine combined with esketamine premedication in children undergoing dental surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044588

Enrollment

Unknown

Registered

2021-03-24

Start date

2021-06-03

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

control group:intranasal administration of dexmedetomidine

experimental group:intranasal administration of dexmedetomidine combined with esketamine

Eligibility

Sex/Gender

All

Age

2 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Those who are scheduled for elective dental surgery under general anesthesia; 2. Aged >=2 and <= 6 , no gender limit; 3. American Society of Anesthesiologists (ASA) physical status I or II; 4. to be able to give informed consent.

Exclusion criteria

Exclusion criteria: 1. Children with allergy to dexmedetomidine or esketamine; 2. Children with acute upper respiratory infection, a history of asthma; 3. Children with a history of chronic illness,cardiac dysrhythmias , prematurity or developmental delay; 4. Children with a history of mental illness.

Design outcomes

Primary

Measure	Time frame
sedation level;dental anxiety level;	—

Secondary

Measure	Time frame
onset of sedation;acceptance of mask induction;emergence delirium;postoperative pain intensity;length of stay in the PACU;haert rate;SpO2;	—

Countries

China

Contacts

Public ContactXing Na

The First Affiliated Hospital of Zhengzhou University

16427485@qq.com+86 13949095172

Outcome results