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Clinical application of phloroglucinol in patients during intensive gastroscopy

Clinical application of phloroglucinol in patients during intensive gastroscopy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044575
Enrollment
Unknown
Registered
2021-03-24
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive gastroscopy

Interventions

phloroglucinol:Phloroglucinol 40 mg was injected intramuscularly
control group:2 ml normal saline was injected intramuscularly

Sponsors

The Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients were 20 years or older and required follow-up for confirmed or suspected upper GI disease. (2) Volunteered to participate in the clinical trial and signed the informed consent.

Exclusion criteria

Exclusion criteria: (1) Previous surgery involving the upper GI tract, (2) severe gastric stenosis or deformation, (3) reflux esophagitis (Los Angeles classification B, C, or D), (4) active gastric or duodenal ulcer, and (5) receiving treatment for cancer (chemotherapy or radiotherapy). In addition, to ensure safety, the following exclusion criteria were also applied: (6) reduced cardiac function (New York Heart Association cardiac function classification grade III or higher), (7) upper GI bleeding requiring hemostasis, (8) a history of shock or hypersensitivity to phloroglucinol, and (9) women who were pregnant or nursing infants were also excluded.

Design outcomes

Primary

MeasureTime frame
the antiperistaltic effect of phloroglucinol;

Secondary

MeasureTime frame
the impact of phloroglucinol on detection rate of gastric lesions;adverse drug reactions;

Countries

China

Contacts

Public ContactChen Xia

The Affiliated Hospital of Southwest Medical University

970217858@qq.com+86 13982764280

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026