the effect of multi-model drug administration on the incidence of cough during emergence period in patients undergoing nasal endoscopic surgery

the effect of multimodel drug administration on the incidence of cough during emergence period in patients undergoing nasal endoscopic surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044573

Enrollment

Unknown

Registered

2021-03-24

Start date

2021-03-15

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cough during emergence period

Interventions

control group:rutine treatment

Intravenous drug combination group:Before endotracheal intubation, normal saline 3ml is sprayed to the surface of the larynx and trachea through laryngeal anesthesia under video laryngoscope, After th

multi-model administration group:Before endotracheal intubation, 0.5%ropivacaine 3ml is sprayed to the surface of the larynx and trachea through laryngeal anesthesia under video laryngoscope, After t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Age between 18-65 years; 2.ASA I~II; 3.Endoscopic nasal surgery under general anesthesia; 4.Operation time 30 to 180 minutes.

Exclusion criteria

Exclusion criteria: 1.Patients refuse to participant; 2.Expected difficulty in tracheal intubation; 3.Complicated with respiratory disease or recent respiratory infection; 4.High risk of perioperative gastric content regurgitation and aspiration.

Design outcomes

Primary

Measure	Time frame
degree of cough;	—

Secondary

Measure	Time frame
extubation time;sore throat score;postoperative complication;	—

Countries

China

Contacts

Public ContactJing Xu

Peking University First Hospital

xymz2005xujing@163.com+86 15201286432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026