Effects of Esketamine on hyperalgesia in patients after cesarean section under General Anesthesia

Observing the effect of ketamine in preventing postoperative hyperalgesia induced by remifentanil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044571

Enrollment

Unknown

Registered

2021-03-24

Start date

2021-03-22

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean section

Interventions

control group:Blank control

experimental group:s-ketamine

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Pregnancy >= 37 w, ASA I - II level, ages 18 to 40 years old, 18 kg/m2 <= BMI <= 30 kg/m2.

Exclusion criteria

Exclusion criteria: Liver and kidney insufficiency, history of alcohol or drug addiction, allergy to or contraindication to ketamine, history of mental illness and cardiovascular disease.

Design outcomes

Primary

Measure	Time frame
Time to first need analgesic treatment;Mechanical pain threshold and pain area;	—

Secondary

Measure	Time frame
Static and dynamic VAS scores;adverse reaction;	—

Countries

China

Contacts

Public ContactLi Huixin

The First Affiliated Hospital of Zhengzhou University

lihuixin0321@163.com+86 15038155760

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026