Epigastric surgery
Conditions
Interventions
control group:propofol
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Agree to participate in the study and sign the informed consent; (2) Aged >= 65 years (3) ASA class I~ III; (4) 18 kg/m2 <= BMI <=30 kg/m2.
Exclusion criteria
Exclusion criteria: (1) Patients allergic to benzodiazepines or dexmedetomidine; (2) Schizophrenia, epilepsy, Parkinson's disease and other neuropsychiatric diseases before surgery; (3) Unable to complete preoperative neuropsychological assessment (MMSE score <= 24 points); (4) Any cerebrovascular accidents, such as stroke and transient ischemic attack (TIA), occurred within 3 months; (5) Abuse history of sedatives, antidepressants and psychoactive drugs, and alcohol abuse; (6) The liver and kidney and other important organs are severely impaired; (7) Other researchers consider it inappropriate to be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic variability;Anesthesia Recovery Time;adverse reaction; | — |
Countries
China
Contacts
Public ContactLi Huixin
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed