Application study of goal-directed sodium reduction treatment in hypernatremia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044564

Enrollment

Unknown

Registered

2021-03-24

Start date

2021-03-21

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypernatremia

Interventions

experimental group:Adjust infusion speed

control group:Traditional sodium lowering therapy

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Aged >n18 years; (2) Serum sodium > 155mmol/L; (3) Normal urine volume and good diuretic response; (4) Patients with prerenal oliguria whose urine volume can be recovered after fluid rehydration.

Exclusion criteria

Exclusion criteria: (1) Patients with continuous renal replacement therapy (CRRT); (2) Patients with diabetes insipidus whose urine volume cannot be controlled; (3) Acute kidney injury (AKI) patients with no response to fluid rehydration or diuretics; (4) Patients with uremia; (5) Patients with heart failure; (6) The calculated liquid inflow is greater than 500ml/h; (7) Diabetic patients with poor insulin response and stubbornly elevated blood sugar.

Design outcomes

Primary

Measure	Time frame
Serum sodium;urine;CVP;	—

Countries

China

Contacts

Public ContactRongli Yang

Dalian Municipal Central Hospital

yever3000@yeah.net+86 15904963796

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026