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Early warning prevention and control strategies to reduce perioperative venous thromboembolism in patients with gastrointestinal cancer: a comparative retrospective cohort study

Early warning prevention and control strategies to reduce perioperative venous thromboembolism in patients with gastrointestinal cancer: a comparative retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044555
Enrollment
Unknown
Registered
2021-03-24
Start date
2018-01-01
Completion date
Unknown
Last updated
2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal tumor

Interventions

Control group:According to the evaluation of VTE thrombosis, the patients were given graded prevention
Experimental group:1.Set up VTE prevention and control team
2.Building VTE knowledge training system
3. Optimize VTE early warning process
4. Standardize the implementation of VTE prevention and control nursing measures

Sponsors

Kunshan Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: This was a retrospective comparativecohort study of patients who underwent gastrointestinal surgery for a gastrointestinal cancer between January 2016 and December 2019 at the Kunshan Traditional Chinese Medicine Hospital of Jiangsu Province Affiliated to Nanjing University of Traditional Chinese Medicine. The surgical oncology department of this hospital has 160 beds, and about 150 patients with gastrointestinal cancer are treated each year. This study was approved by the Medical Ethics Committee of the Kunshan Traditional Chinese Medicine Hospital,Jiangsu Province, Affiliated to the Nanjing University of Traditional Chinese Medicine (#2017063). The requirement for informed consent was waived. The inclusion criteria were as follows: 1) patients >=18 years of age; 2) those who underwent laparotomic or laparoscopic gastrointestinal tumor resection under general anesthesia; 3) patients with complete data, including pathological or cytological diagnosis of malignant tumor; 4) TNM stages I–III; 5) no history of anticoagulation therapy during the 3 months before surgery; 6) no neoadjuvant chemoradiotherapy; 7) patients had the ability to communicate normally.

Exclusion criteria

Exclusion criteria: 1) Patients with cardiopulmonary diseases or nerve, muscle, or joint diseases, or any condition that affected mobility; 2) mental illness or severe cognitive disorders or defects in language expression; 3) postoperative cardiac, cerebrovascular, or other severe complications; 4) VTE before surgery; 5) contraindications to drugs or physical VTE prevention; 6) patients who were using heparin, low-molecular-weight heparin, or oral anticoagulants; 7) patients who were discharged from hospital after surgery against medical advice or were lost to follow-up; 8) were transferred to a local hospital for additional treatments after surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of DVT;The correct rate of VTE evaluation and the standard implementation rate of VTE preventive measures;The coagulation indicators included plasma D-dimer, prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen degradation products;

Secondary

MeasureTime frame
VTE knowledge of nurses;

Countries

China

Contacts

Public ContactLu Yun

Kunshan Hospital of Traditional Chinese Medicine

ksluyun@126.com+86 13913262392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026