Effect of artificial tears on corneal curvature and visual quality before refractive surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044501

Enrollment

Unknown

Registered

2021-03-23

Start date

2021-04-15

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xerophthalmia

Interventions

low concentration group (normal):Drop 1% sodium hyaluronate eye drops

high concentration group (normal):Drop 3% sodium hyaluronate eye drops

low concentration group (dry eye):Drop 1% sodium hyaluronate eye drops

high concentration group (dry eye):Drop 3% sodium hyaluronate eye drops

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients who were examined before refractive surgery and agreed to participate in the experiment.

Exclusion criteria

Exclusion criteria: 1.Any corneal pathology. 2.The use of any eye drops 24 hours before the examination, a necessity for any topical eye therapy. 3.active ocular or nasal allergies,corneal or conjunctival infection. 4.abnormalities of the nasolacrimal drainage apparatus. 5.level 4 dry-eye severity. 6.eyelid deformities. 7.preceding ocular surgery or trauma.

Design outcomes

Primary

Measure	Time frame
Corneal curvature;	—

Secondary

Measure	Time frame
Visual quality;Corneal astigmatism;	—

Countries

China

Contacts

Public ContactWang Jing

Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University

wangjing2980@163.com+86 15056967187

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026