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Effect of preoperative PPI administration on nausea and vomiting after sleeve gastrectomy: a prospective randomized controlled study

Effect of preoperative PPI administration on nausea and vomiting after sleeve gastrectomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044485
Enrollment
Unknown
Registered
2021-03-23
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity and Metabolic Disorders

Interventions

Experimental group:Preoperative PPI
Control group:Nil

Sponsors

The First Affiliated Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) BMI of > 35 kg/m2 or BMI of 27.5-34.9 kg/m2 with poor blood glucose control after lifestyle changes and medication, or with more than 2 other metabolic diseases; (2) The American Society of Anesthesiologists (American Society of Anesthesiologists, ASA) class I - II; (3) Patients aged 18-65 years, with full understanding, agree to participate in this study. (4) Signing the Informed Consent.

Exclusion criteria

Exclusion criteria: (1) Patients with preoperative severe liver and kidney insufficiency, cardiopulmonary insufficiency, or other serious diseases that did not receive standard treatment; (2) Patients with a history of severe mental illness or/or gastrointestinal surgery; (3) Lack of willingness and motivation to accept postoperative lifestyle changes; (4) Clinical evaluation was severe GERD; (5) Patients who took opioids, anti-inflammatory hormones and antiemetic drugs 24 hours before surgery.

Design outcomes

Primary

MeasureTime frame
Visual analog scale of nausea;Verbal numeric scale of pain;

Countries

China

Contacts

Public ContactZhiyong Dong

The First Affiliated Hospital of Jinan University

dongzy2008@jnu.edu.cn+86-20-38688735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026